A coordinated, comprehensive approach to early intervention has the potential to promote optimal development and create a brighter future for young children at risk or with disabilities and their families living in poverty. This article outlines the relationship between Early Head Start (EHS) and early intervention (EI) in the areas of child find, individualized planning and service delivery, family support, transition, and community partnerships. Evaluation findings and recommendations from the SpecialQuest work with more than 500 EHS and EI programs throughout the United States between 1997 and 2010 highlight the importance of relationship building between programs, shared learning opportunities, a shared vision, family and community engagement, time for collaboration, administrative support, and continuous improvement. (author abstract)