Parents and caregivers have struggled to arrange childcare throughout the COVID-19 pandemic, and early evidence suggests negative effects on caregiver employment. However, analyses have not compared pre–COVID-19 and post–COVID-19 periods or stratified estimates by children’s health care needs. Forgoing employment is more common among caregivers of children with special health care needs (CSHCN). We estimate childcare-related employment disruptions before and after COVID-19, accounting for CSHCN status and sociodemographic factors. (author abstract)