The Difficulties in Emotion Regulation Scale (DERS; Gratz & Roemer, 2004) was developed to assess emotion dysregulation more comprehensively than existing measures. The initial 41 items were developed and selected on the basis of numerous conversations with colleagues well versed in the emotion regulation literature. The Generalized Expectancy for Negative Mood Regulation Scale (NMR; Catanzaro & Mearns, 1990) was used as a template and helped to structure the format (though not the content) of some of the items. The initial measure was tested in samples of 18-55 yr old undergraduate students in the US. Factor analyses and item reduction processes resulted in 36 final items distributed across 6 factors: Nonacceptance of Emotional Responses (e.g., When I'm upset, I feel like I am weak); Difficulties Engaging in Goal-Directed Behavior (e.g., When I'm upset, I can still get things done); Impulse Control Difficulties (e.g., When I'm upset, I feel out of control); Lack of Emotional Awareness (e.g., I pay attention to how I feel [r]); Limited Access to Emotion Regulation Strategies (e.g., When I'm upset, it takes me a long time to feel better); and Lack of Emotional Clarity (e.g., I am confused about how I feel). Preliminary findings suggest that the DERS has high internal consistency, good test–retest reliability, and adequate construct and predictive validity. (PsycTests Database Record (c) 2021 APA, all rights reserved)