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This document is relevant for researchers interested in using the National Survey of Early Care and Education (NSECE) to carry out analysis of local-level interaction of supply and demand of early care and education. This user guide briefly describes key elements of the NSECE sampling methodology, including Primary Sampling Units (PSU) for the household and listed center- based and home-based providers, Secondary Sampling Units (SSU) for the household sample, and the Provider Cluster. The user guide explains how to create PSU- and cluster-level aggregate measures and how to appropriately use PSU and Provider Cluster Weights to generate estimates for sub-national geographic areas.