First 5 LA's 2015-2020 Strategic Plan aims to improve outcomes for the greatest number of children prenatal to 5 in Los Angeles County by working with partners to strengthen families, build community capacity, increase access to high quality early care and education, and help ensure health services meet the needs of young children and their families. In order to maximize potential impact of its investments, First 5 LA is committed to being a learning organization and sharing lessons learned through research and reflection, so that best practices can be replicated and course corrections made if need be to improve the quality of services and support systems for young children and their families throughout L.A. County. This research brief summarizes key findings from research on the outcomes of First 5 LA's investment in Los Angeles Universal Preschool's programs. Our hope is that lessons learned from these efforts will have a multiplier effect and help policymakers and practitioners improve the quality of early child care and education throughout the county, so that all children can enter kindergarten ready to achieve in school and life. (author abstract)