This study included data from two large samples to examine the psychometric properties of the Parent-Child Rating Scale (P-CRS), which was designed to measure children's social-emotional development. A local urban sample of parents of 1,332 children (aged 3 to 6) and parents of 1,213 children from a national panel (aged 3 to 5) completed the P-CRS. Consistent psychometric properties of the P-CRS were found from both samples. Exploratory factor analysis revealed 7 domains of social-emotional development; Negative Peer Social Relations, Positive Peer Social Relations, Task Orientation, Emotional Sensitivity/Anxiety, Self Reliance, Frustration Tolerance, and Positive Disposition. The P-CRS demonstrated excellent internal reliability and evidence of criterion validity against teacher's ratings of development and parental report of health and developmental problems (e.g., ADHD and Autism). The P-CRS is a psychometrically valid and user-friendly questionnaire that could potentially help schools, researchers, and pediatricians assess children's social-emotional development. (author abstract)