This guide outlines key design, financing, and policy considerations for developers, policymakers, and providers to support enhanced and coordinated efforts to co-locate family child care with affordable housing. Following initial sections framing opportunities and best practices in design, four scenarios are presented on the most common examples of co-location. Each scenario includes considerations and best practices for the design and development processes, a case study of a place or development that has deployed the strategy, and policy considerations focused on easing and incentivizing future efforts to co-locate. (author abstract)