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Interagency Meeting on Subgroup Analysis

Subgroup analysis, broadly, aims to measure change within and between groups. The challenges in designing research to examine subgroups, the analysis of the data and the interpretation of the results are critically important to answer the question that comes up most regularly in policy-relevant research: What works for whom? In September 2009 the Administration for Children and Families, along with other federal partners convened a meeting of experts to discuss the state of the field. Presentations at the meeting centered on innovative methods for conducting subgroup analysis and a discussion of guidelines for interpretation and reporting of subgroup analyses in prevention and intervention research.

Introduction

Naomi Goldstein, ACF
Setting the Stage for the Interagency Meeting on Subgroup Analysis
download this video (.wmv 17MB, with captions)

Panel 1 Overview: Laying out the State of the Field

Talk 1 — Rui Wang
Overview of Subgroup Analyses in Medical and Public Health Research
download video (.wmv 95MB, with captions)

Talk 2 — Jacob Klerman
Subgroups Analysis: A View from the Trenches
download video (.wmv 110MB, with captions)

Panel 1 Q & A
download video (.wmv 44MB, with captions)

Panel 2: Framing Questions, Design & Analysis

Talk 1 — Hendricks Brown
Foundational Issues in Examining "Subgroup" Effects in Experiments
download video (.wmv 95MB, with captions)

Talk 2 — David MacKinnon
Simultaneous Mediation and Moderation Tests: Examining Mediation in Subgroups
download video (.wmv 57MB, with captions)

Panel 2 Q & A (Talks 1 and 2)
download video (.wmv 49MB, with captions)

Talk 3 — Jennifer Hill, Andrew Gelman and Masanao Yajima
Why we (usually) don't need to worry about multiple comparisons
download video (.wmv 88MB, with captions)

Talk 4 — Michael Borenstein
Meta-Analysis and Subgroups
download video (.wmv 17MB, with captions)

Talk 5 — Stephanie Lanza and Bethany Rhoades
Subgroup analysis from a latent class analysis approach
download video (.wmv 104MB, with captions)

Panel 2 Q&A (Talks 3, 4, 5)
download video (.wmv 67MB, with captions)

Talk 6 — Al Farrell and David Henry
Moderators of Effects at Multiple Ecological Levels: Examples from Youth Violence Prevention Trials
download video (.wmv 102MB, with captions)

Talk 7 — Daniel Almirall, Beth Ann Griffin, Andrew Morral, and Thomas Ten Have
Causal Effect Moderation (Modification) When Treatment or Exposure is Time-Varying
download video (.wmv 86MB, with captions)

Talk 8 — Marianne Bitler
Quantile regression and subgroups
download video (.wmv 77MB, with captions)

Panel 2 Q &A (Talks 6, 7, 8)
download video (.wmv 67MB, with captions)

Panel 3: Reporting and Interpreting Subgroup Differences

Talk 1 — Howard Bloom and Charles Michalopolous
When is the Story in the Subgroups?
download video (.wmv 116MB, with captions)

Talk 2 — Cris Price and Rob Olsen
Post-hoc Subgroups
download this video (.wmv 81MB, with captions)

Panel 3 Q & A
download video (.wmv 62MB, with captions)