This literature review synthesizes findings from multiple random assignment experimental evaluations conducted to examine the impacts of various intervention programs with a home visiting component. The goal of this review is to identify programs that work as well as the intervention strategies that contribute to program success. This synthesis examines findings from 66 studies that implemented random assignment intent-to-treat experimental evaluations of programs that include home visiting as a program component. We segmented this analysis by the target population served: 0- to 3-year olds, 4- to 5-year olds, 6- to 11-year olds, and 12- to 17-year olds. While several themes emerge, no one approach, setting, or activity is effective for children across all age groups. (author abstract)